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Fig 1.

Livedo reticularis.

This figure shows an example of a patient with Sneddon syndrome with livedo reticularis on the right arm. This patient also had livedo reticularis on the legs, trunk, buttocks and face.

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Table 1.

Clinical characteristics at diagnosis.

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Fig 2.

Example one of a probable occlusive microangiopathy.

(A) Low magnification shows that the abnormal arteries are located in the deep dermis (box) (H&E, 25x). (B) In detail, multiple arteries with a patent lumen and a thickened vessel wall, suggesting neovascularization (H&E, 100x).

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Fig 3.

Example two of a probable occlusive microangiopathy.

(A) Low magnification shows that the abnormal arteries are located in the deep dermis (box) (H&E, 20x). (B) In detail, extensive neovascularization (*) and recanalization (^) are visible (H&E, 200x).

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Fig 4.

Example of a livedo pattern.

The right side of the biopsy shows a normal superficial dermis. On the left side of the biopsy, a livedo pattern is visible (arrow). There are more arteries in the superficial dermis, which are more horizontally arranged (H&E, 50x).

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Table 2.

Histology findings.

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Table 2 Expand

Table 3.

Test characteristics of the skin biopsy.

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