Abstract
Mesenteric cysts are a rare occurrence in clinical practice, and even fewer are found to be of Mullerian origin. Diagnosis of mesenteric cysts is typically based on clinical assessment and radiological imaging. Surgical excision remains the primary treatment option. We report a case of a middle-aged lady presenting with a giant mesenteric cyst weighing 8-kilogrammes that was managed with laparotomy. Current literature of this rare clinical entity was also reviewed, including differential diagnoses of cystic lesions within the abdomen and role of imaging in guiding pre-operative diagnosis and management strategies. The giant mesenteric cyst was successfully excised en bloc without spillage via a laparotomy. Analgesia optimisation was achieved with a continuous local anaesthetic infusion. Pre-operative radiology can assist in diagnosis of the mesenteric cyst and guide management. Should an open surgical approach be selected, analgesia can be optimised with a continuous local anaesthetic infusion which decreases need for opioid medications.
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References
Kurtz R, Heimann T, Beck A, Holt J. Mesenteric and retroperitoneal cysts. Ann Surg. 1986;203(1):109–12.
Tan J, Tan K, Chew S. Mesenteric cysts: an institution experience over 14 years and review of literature. World J Surg. 2009;33(9):1961–5.
Caropreso P. Mesenteric cysts. Arch Surg. 1974;108(2):242.
Dursun H, Albayrak F, Yildirim R, Uyanik A, Yilmaz O, Okcu N, et al. Giant mesenteric cyst can present as pseudoascites with raised Ca125. Turk J Gastroenterol. 2009;20(4):305–6.
Ma A, Ayre K, Wijeyekoon S. Giant mesenteric cyst: a rare cause of abdominal distension diagnosed with CT and managed with ultrasound-guided drainage. BMJ Case Rep. 2012 Sep 3;2012:bcr0220125916.
Beahrs O, Judd E, Dockerty M. Chylous cysts of the abdomen. Surg Clis of North America. 1950;30(4):1081–96.
Yacoub J, Clark J, Paal E, Manning M. Approach to cystic lesions in the abdomen and pelvis, with radiologic-pathologic correlation. Radiographics. 2021;41(5):1368–86.
De Perrot M, Bründler M, Tötsch M, Mentha G, Morel P. Mesenteric cysts. Dig Surg. 2000;17(4):323–8.
Guraya S, Salman S, Almaramhy H. Giant mesenteric cyst. Clinics and Practice. 2011;1(4):237–8.
Isaia M, Erodotou M, Nakos G, Nikolaou N. Complete surgical enucleation of a giant chylous mesenteric cyst. Case Reports in Surgery. 2020;2020:1–3.
Boghossian S, Dasgupta K, Haugk B, White S. Müllerian cyst of the mesentery: a case report of an unusual location. Clin Anat. 2010;23(7):866–9.
Inatsuchi H, Masuda A, Katsuoka Y, Hihara T, Murakami Y. Giant Müllerian duct cyst: a case report. Hinyokika Kiyo. 1991;37:1719–22.
Thomas-de-Montpréville V, Dulmet E. Cysts of the posterior mediastinum showing Müllerian differentiation (Hattori’s cysts). Ann Diagn Pathol. 2007;11(6):417–20.
Lee J, Song S, Park C, Kim B. Müllerian cysts of the mesentery and retroperitoneum: a case report and literature review. Pathol Int. 1998;48(11):902–6.
Kondi-Pafiti A, Papadias K, Kairi-Vassilatou E, Chatzistamou-Kiari I, Kontogianni K, Smyrniotis V. Extraovarian mullerian-type cystic tumors of the female A report of six cases and review of the literature. Eur J Gynaecol Oncol. 2004;25(5):657–9.
Harpaz N, Gellman E. Urogenital mesenteric cyst with fallopian tubal features. Arch Pathol Lab Med. 1987;111(1):78–80.
Mokhtari M, Kumar PV. Cytologic findings of urogenital mesenteric cyst. Arch Iran Med. 2013;16(7):436–8.
Yohendran J, Diaz MM, Eckstein R, Wilson T. Benign retroperitoneal cyst of Mullerian type. Asian J Surg. 2004;27(4):333–5.
Olat C, Özaçmak İ, Yücel T, Özmen V. Laparoscopic resection of giant mesenteric cyst. J Laparoendosc Adv Surg Tech. 2000;10(6):337–9.
Liew S, Glenn D, Storey D. Mesenteric cyst. ANZ J Surg. 1994;64(11):741–4.
Shamiyeh A, Rieger R, Schrenk P, Wayand W. Role of laparoscopic surgery in treatment of mesenteric cysts. Surg Endosc. 1999;13(9):937–9.
Lucey B, Kuligowska E. Radiologic management of cysts in the abdomen and pelvis. Am J Roentgenol. 2006;186(2):562–73.
Shimura H, Ueda J, Ogawa Y, Ichimiya H, Tanaka M. Total excision of mesenteric cysts by laparoscopic surgery: report of two cases. Surg LaparoS Endos Percutaneous Techniques. 1997;7(2):173–6.
Vu JH, Thomas EL, Spencer DD. Laparoscopic management of mesenteric cyst. Am Surg. 1999;65(3):264–5.
Chan D, Goh R, Keh C. Continuous wound infusion with ropivacaine alone provides adequate analgesia following laparotomy. Langenbeck’s Archives of Surgery. 2021;406(2):413–8.
Acknowledgements
The authors would like to thank Dr. Seet Ju Ee from the Department of Pathology, National University Hospital for her expert opinion in the pathological diagnosis of the surgical specimen.
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Leong, E.K.F., Lee, J.W.K. & Keh, C.H.L. Eight-Kilogramme Giant Mesenteric Cyst of Mullerian Origin: Case Report and Review of Literature. SN Compr. Clin. Med. 4, 241 (2022). https://doi.org/10.1007/s42399-022-01315-w
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DOI: https://doi.org/10.1007/s42399-022-01315-w